Regional PI Associations, or RPAs, represent PI around the world. Currently there are 27 of these local organisations in the following countries:

For members, the local RPA is the personal point of contact. RPAs have to meet a set of criteria laid down by PI and are responsible for building their own membership. They are also responsible for in-country activities promoting the PROFIBUS and PROFINET brands and technologies. These activities include marketing, trade fairs, seminars, workshops and press conferences, as well as local publications particularly where translations are needed. RPAs are a great 'first point of contact' for new developers and users.

RPAs maintain a close relationship with other localized activities, including PI Competence Centers (PICCs), Test Labs and Training Centers. Several times a year, RPAs meet to discuss common issues and be updated on latest developments.